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ahr pathway Elevated homocysteine has been considered to be
2019-10-16
Elevated homocysteine has been considered to be a risk factor for vascular dysfunction, vascular disease, and preeclampsia , . The methionine-homocysteine metabolism is responsible for supplying COMT with the methyl-group donor (-adenosyl methionine; SAM) necessary for 2-ME synthesis, and alteratio
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It is common for plants that are
2019-10-16
It is common for plants that are deficient in P to invest in their roots in order to maximise P uptake from the soil. Here, plants grown in soil amended with OA had a higher root biomass:shoot Castanospermine ratio compared with plants in the INORG-P treatment. Additionally, greater allocation of C
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xmu Form the previous literature It was observed that RHA
2019-10-16
Form the previous literature, It was observed that RHA was burnt in the range of 500 °C to 700 °C, with high content of quartzite silica was used is a partial replacement of cement in mortar and in concrete. The results shown an excellent behavior in enhancing the mechanical properties of cement mor
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For immobilization of enzymes natural polymers depict severa
2019-10-15
For immobilization of enzymes, natural polymers depict several outstanding features as support. These materials are inert, non-toxic, biodegradable and biocompatible. As well as, they can be treated with different functional groups easily by chemical reactions that occur under gentle conditions in a
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The total reduced glutathione content was determined in both
2019-10-15
The total reduced glutathione content was determined in both 97 9 to examine whether retinol was decreasing glutathione concentrations and thus decreasing the conjugation of NAPQI. Total hepatic (3.9±0.3 vs 4.9±1.0 μmol/g, retinol vs untreated, respectively) and renal (0.4±0.1 vs 0.2±0.1 μmol/g, re
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Everolimus treatment showed an increase in the number
2019-10-15
Everolimus treatment showed an increase in the number of plaques and a reduction in plaque size, depending on concentration and treatment time (Fig. 1, Fig. 2). Everolimus-pretreated train ride adsorbed less virus with more plaque formation in the initial phase of infection (Fig. 3). The ability an
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Indeed a significant difference was
2019-10-15
Indeed, a significant difference was observed for the binding of glycated α-synuclein. Thus, g-α-synuclein bound to other part of GAPDH in 4 of 10 simulations (Fig. 2F, brown, yellow and dark-green chains, and Fig. 2G, brown chain). This additional binding site is located on the interface between O
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br Results br Discussion MSCs derived from the bone
2019-10-15
Results Discussion MSCs derived from the bone marrow and adipose tissue have been shown to promote the growth and metastatic ability of breast cancer and other human malignancies, but the mechanisms are incompletely understood (Barcellos-Hoff et al., 2013, Cuiffo et al., 2014, Del Pozo Martin
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Our results suggest that formation of DDR
2019-10-15
Our results suggest that formation of DDR1b clusters may be important for and precede receptor phosphorylation. Indeed, while DDR1b clustering was readily detected (by YFP signal) 30 min after collagen administration, phosphorylated DDR1 species at Y513 (present in the IJXM) were evident after 4 h o
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In this study it was noted that two out
2019-10-15
In this study, it was noted that two out of five E. crassus CYPs (CYP5681A1 and CYP5682A1) had no intron, and 3 others had one intron at different positions (Fig. 3). Number and length of introns are varied in diverse species. For example, most hypotricha genes characterized so far lack introns (Pre
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br Conclusion In this work experiments were carried out to
2019-10-15
Conclusion In this work, experiments were carried out to purify the protein with COX activity, using an anti-mouse COX-2 pAb and a COX activity assay as tools for monitoring the protein responsible for this activity in the parasite. Gp63 enrichment through the affinity column and identification b
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br Acknowledgement This work was supported by grant form EU
2019-10-15
Acknowledgement This work was supported by grant form EU (FP7 grant agreement no.: 266033 SPonge Enzyme End Cell for Innovative AppLication-SPECIAL). Introduction Prolyl 4-hydroxylases (P4Hs) have central roles in the synthesis of collagens and the regulation of oxygen homeostasis [1]. The po
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N1-Methylguanosine-5\'-Triphosphate In general terms PLA
2019-10-15
In general terms, PLA2s participate in the Lands cycle of phospholipid fatty N1-Methylguanosine-5\'-Triphosphate recycling [1,15,25], whereby the fatty acid composition at the sn-2 position of phospholipids is tightly controlled by a balance between hydrolytic reactions mediated by PLA2s versus acti
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SB 225002 LVDP values of at the end of reperfusion L
2019-10-15
LVDP values of ~80% at the end of reperfusion. L-NAME treatment did not modify the contractility detected in ischemic control hearts but annulled the actions of BZ acquiring LVDP values up to 40% (Fig. 4 A). A similar pattern was observed when +dP/dtmax was analysed (Fig. 4 B). LVEDP, as an index o
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Similarly EGCG restored the mitochondrial
2019-10-14
Similarly, EGCG restored the mitochondrial energy shortfall in fibroblasts and lymphoblasts of the patients affected by Down syndrome, even so the mechanism of the effect was not clearly known (Valenti et al., 2013). EGCG also stimulated the mitochondrial biogenesis by activation of nuclear respirat
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