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In silico prediction software SIFT PolyPhen
2019-05-21
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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The results of our initial cross
2019-05-21
The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t
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ion channel Adem s las situaciones en las que Nicol s se
2019-05-21
Además, las situaciones en las que Nicolás se encuentra con las piedras, sus dudas en torno ion channel si son piedras-huesos o simples piedras, sus caminatas por cerros, encrucijadas y pueblos más o menos fantasmales, las respuestas diferentes a sus preguntas por Pedro Páramo (“¿se acuerda que yo q
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Findings from the last major
2019-05-21
Findings from the last major systematic review of the global prevalence of echocardiographic rheumatic GDC-0994 disease showed that the highest calculated regional prevalence was in sub-Saharan Africa (5·7 cases per 1000 people), indigenous people in the Pacific islands, Australia, and New Zealand
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Sin embargo esta intervenci n del Estado en
2019-05-21
Sin embargo, esta intervención del Estado en asuntos culturales es propia de una etapa anterior JNJ-26481585 cost los incontenibles procesos de modernización y democratización de la sociedad latinoamericana. De acuerdo con José Luis Romero, desde 1880, las nuevas relaciones entre los países industri
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purchase V5 Epitope The studies from several laboratories su
2019-05-21
The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi
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Patients with heart failure are
2019-05-20
Patients with heart failure are at a high risk of mortality and morbidity. Medical expenses associated with heart failure are increasing, and approaches aimed at early heart failure detection and reduction of the hospitalization rate are yet to be developed. Patients with CIEDs also develop heart fa
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Our results are consistent with previous findings
2019-05-20
Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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br It s that time of year again when we
2019-05-20
It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations.
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A year old woman was referred to our
2019-05-20
A 77-year-old woman was referred to our medical center for second opinion for refractory CMML-2. She had been incidentally found to have mild leukocytosis, anemia, and thrombocytosis on routine laboratory analysis. At diagnosis her white blood cell count (WBC) was 12×10/L, hemoglobin was 10.8g/dL, a
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Evidence based interventions that are theory
2019-05-20
Evidence based interventions that are theory driven and accessible within the local culture are do-able and do not need to rely on imported interventions—especially when those are costly. Many bereaved children and youth reside in the Okadaic acid and have little recourse to good psychosocial suppo
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VV optimization From the foregoing discussion it is clear th
2019-05-20
VV optimization From the foregoing discussion, it is clear that AV delay programming to ensure ventricular preexcitation with optimal LV diastolic filling and systolic function is complex, and the optimal method that translates into improved patient outcomes is uncertain. These issues are even more
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Y es que en Estados Unidos el campo denominado
2019-05-20
Y es que, en Estados Unidos, el campo denominado Cultural Studies producía una gran cantidad de investigaciones sobre la región mediante categorías de análisis propias del llamado primer mundo. En su versión latinoamericana, los Estudios Culturales llegaron cgrp antagonist consolidarse en los años 1
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We also demonstrated by ELISA ELISPOT and CTL assays the
2019-05-20
We also demonstrated by ELISA, ELISPOT and CTL assays the capacity of alum to induce a Th1 immune response. The evaluation of the ICG001 response against LALF32-51 peptide, E7 protein and LALF32-51-E7 fusion protein in immunized mice suggest that the antibodies response generated by the immunization
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br The slow progress in
2019-05-18
The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020;
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