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To evaluate the visual comfort in
2018-10-22
To evaluate the visual comfort in this order Puromycin case, the Daylight Glare Probability (DGP) (Wienold and Christoffersen, 2006) was used as an indicator, which can be expressed as follows:where E is the total vertical eye illuminance [lx], is the solid angle of the glare source [sr], L is the
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The year survival rate for patients with pulmonary EHE is
2018-10-22
The 5-year survival rate for patients with pulmonary EHE is about 60% (range, 45–71%). The presence of anemia, weight loss, pulmonary symptoms, and especially hemorrhagic effusion, are associated with poorer prognoses. In our series, Patient 1 had no significant history of poor prognostic factors. H
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The mechanisms of abdominal blunt trauma
2018-10-22
The mechanisms of abdominal blunt trauma, that cause intestinal perforation in the hernia sac, have received various explanations. Reynolds asserted that direct trauma to an inguinal hernia can produce enough pressure to cause perforation of the intestinal walls. A study by O’Leary and MacGregor sho
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Surgery and targeted molecular therapy
2018-10-22
Surgery and targeted molecular therapy are the two gold standards for GISTs. Surgery is the first choice if a complete resection is possible. Imatinib is indicated for treating patients with KIT-positive (i.e., CD117-positive) unresectable and/or metastatic GISTs. For KIT-mutant proteins, imatinib i
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Arachnoid thickening as a possible
2018-10-22
Arachnoid thickening as a possible factor for typical TN has seldom been reported. We observed two cases (7.7%) of arachnoid thickening that appeared to be associated with neuralgia development. After adhesiolysis, the immediate postoperative outcome was excellent and good in the two cases. Ishikawa
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br Materials and methods br Results
2018-10-22
Materials and methods Results and discussion The dose-dependent inhibition of HMG-CoA reductase activity by the extracts as presented in Fig. 1 and the IC50 values in Table 1 showed that there was no significant (P>0.05) difference in the inhibitory abilities of the two extracts. The control o
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A study by Hu et al examined the
2018-10-22
A study by Hu et al. [59] examined the effects of combined fucoxanthin and conjugated linoleic eukaryotic initiation factor on high-fat diet-induced obesity in rats. The animals were fed a high-fat diet (control), supplemented with two doses of fucoxanthin or low-dose fucoxanthin plus conjugated lin
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We next aimed to test the differentiation capabilities
2018-10-22
We next aimed to test the differentiation capabilities of the EZ spheres. We found that at any passage for all cell lines regardless of cryopreservation, EZ spheres can be placed in specific neural induction media for terminal neuronal or glial cell differentiation using protocols adapted from those
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br Results br Discussion Controlling the chromosome
2018-10-22
Results Discussion Controlling the chromosome stability of hESCs and their derivatives remains a fundamental challenge in trials of hESC derivative-based cell therapy. In 2004, Andrew and co-workers reported that chromosomal instability during extensive hESC expansion was due to the monensin
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In summary our work is an important step to
2018-10-22
In summary, our work is an important step to understand and to control phosphorylation dynamics in human pluripotent stem cell maintenance and differentiation. This is the first report that provides a detailed analysis of MAPKs regulation in hESC in response to a small molecule inhibitor. We have sh
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Thus it is worth mentioning
2018-10-22
Thus, it is worth mentioning that none of these aforementioned studies undoubtedly provide a definitive answer concerning the potential origin of HSCs in the mouse embryo. To add to the complexity, it is possible, as shown in the Xenopus embryo (Turpen et al., 1997) and suggested in mouse (Matsuoka
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The use of a novel Pax
2018-10-22
The use of a novel Pax9Venus reporter PSC line allowed the purification of PSC-derived Pax9+ AFE for molecular analysis and enabled the comparison to embryonic Pax9+ AFE. The expression of several pharyngeal endoderm transcription factors in PSC-derived Pax9+ AFE suggests that these Cy3.5 hydrazide
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br Experimental Procedures Briefly hiPSCs were generated fro
2018-10-22
Experimental Procedures Briefly, hiPSCs were generated from IMR90, CCD-1097SK, BJ1, and NPC cells derived from 11-week-old fetal brain using retroviral expression of OCT4, SOX2, KLF4, and c-MYC or OCT4, NANOG, KLF4, and LIN-28. This study of hESCs and hiPSCs was approved by the UCLA Embryonic Ste
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br Results br Discussion FXR was initially shown to regulate
2018-10-22
Results Discussion FXRα was initially shown to regulate the enterohepatic cycle and BA biosynthesis. In recent decades, many studies have demonstrated its involvement in other physiological functions (digestion, immunity) and diseases such as diabetes and cancer. FXRα participates in the homeo
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This finding is consistent with our observations
2018-10-22
This finding is consistent with our observations in human fetal RG cells (Mo and Zecevic, 2008), indicating that in both cell populations Pax6 affects proliferation as well as neuronal fate. Numerous studies have reported the successful transplantation of hESC into rodent brains (Kelly et al., 2004
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