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By IF we detected an overall increase in tau
2018-10-24
By IF we detected an overall increase in tau in A152T neurons, with particular accumulation of P-tau in the cell body, consistent with somatodendritic redistribution of tau, as described for tauopathies and Alzheimer’s disease (de Calignon et al., 2012; Fong et al., 2013; Li et al., 2011; Sydow et a
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Our data related to C orf mRNA
2018-10-24
Our data related to C9orf72 mRNA levels conflict with the reports of others, who demonstrate a general reduction in C9orf72 in diseased adenosine receptor (Ciura et al., 2013; Cooper-Knock et al., 2013; Donnelly et al., 2013; Waite et al., 2014; Xi et al., 2013). These discrepancies may stem from th
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Impaired neural migration and defects
2018-10-24
Impaired neural migration and defects in the order glp-2 cytoskeleton are well-known factors contributing to malformations during the cortical development (Pang et al., 2008). Reduced expression of NSUN2 in human NES cells impaired migration toward the chemoattractant FGF2. FGF2 is widely used to m
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Near the emission threshold the disagreement between the mea
2018-10-24
Near the emission threshold, the disagreement between the measured current characteristics and theoretical predictions was often even more notable. Fig. 5 represents a few typical emission plots with the intervals of current saturation and even reduction. Such features were most typical for the emi
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Inequality assumes that there exist
2018-10-24
Inequality (7) assumes that there exist a finite infimum and finite suprema. The H set can be finite or infinite. holds for this x. However, h can depend on x. Taking the infimum and the suprema in inequality (7) eliminates this dependence and still cytoskeleton the inequality valid, as x ≥ 0. Let
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br Convergence study and computational results To adequately
2018-10-24
Convergence study and computational results To adequately choose the size of the finite elements and the integration step, we examined the convergence of the results as a function of these parameters. Given the physical nature of the simulated vibration process, the grid dimension and the integra
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In Ref we considered the
2018-10-24
In Ref. [4], we considered the problem of fullerene growth more elaborately, namely, how to design new fullerenes and their graphs if given a basic elementary graph of a mini-fullerene playing the role of progenitor. We have developed a way of designing different calcium sensing receptor of fulleren
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The reasons for continued low maternal health
2018-10-24
The reasons for continued low maternal health service use are complex, but appear to include high user fees and poor quality of care in many settings (Hatt, Makinen, Madhavan, & Conlon, 2013; Nair et al., 2014). A wide-variety of programs have been introduced to address these barriers including inte
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br Acknowledgement br Introduction The
2018-10-24
Acknowledgement Introduction The world is currently challenged with global warming, depletion of non-renewable fossil fuel and environmental pollution. The major sources of greenhouse gas emissions are fossil fuels (Endalew et al., 2011). To overcome these challenges, there is a need to find a
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Several ongoing clinical trials are evaluating the feasibili
2018-10-23
Several ongoing clinical trials are evaluating the feasibility of combining chemotherapeutic nanomedicines with radiotherapy or small molecule drugs (such as gemcitabine). Pegylated liposomal doxorubicin has shown improved therapeutic efficacy when combined with radiotherapy in several animal studie
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Particulate matter was characterized in
2018-10-23
Particulate matter was characterized in broncho-alveolar lavage fluid (BALF) extracts and in situ in AM of asthmatic Parisian children. Asthmatic patients, rather than healthy subjects, were selected for the study since fiber-optic bronchoscopy with broncho-alveolar lavage is routinely performed in
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br Materials and Methods br
2018-10-23
Materials and Methods Results Discussion Our study demonstrates that applications of BCP extend beyond determination of antibiotic mechanism of action to determination of antibiotic susceptibility and identification of optimally effective combinatorial therapies. This single cell phenotype-
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It is unclear whether the
2018-10-23
It is unclear whether the adipose-derived progenitor induced pluripotent stem cells exert a role in the beneficial effect of the AGTP. Recent data suggested that cardiac adipose-derived progenitors have an inherent cardiac-like phenotype and may support heart homeostasis, perhaps as a cell reservoir
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Stratifying patients according to the toxicity risk and
2018-10-23
Stratifying patients according to the toxicity risk and modulating EBRT dose would provide a valuable tool for personalized EBRT (). Many efforts have been made to develop assays capable of predicting susceptibility for the development of radiation injury that finally allow customization of EBRT pro
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Another methodological issue that can obscure and complicate
2018-10-23
Another methodological issue that can obscure and complicate the assessment of the diet-mental health relationship relates to the covariance between health behaviours such as diet, physical activity and smoking. As these health behaviours are all associated with depression in a bidirectional manner,
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