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Phosphoramidon Disodium Salt In this review focusing on bioc
2021-03-12
In this review, focusing on biocatalyst “formate dehydrogenase FDH” catalyzing both of the formic Phosphoramidon Disodium Salt oxidation to CO2 and the CO2 reduction to formic acid, representative examples of properties, types, structure of active-site of FDH and, reaction mechanism of formic acid
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Presumably LBPs have health promoting activities
2021-03-11
Presumably, LBPs have health-promoting activities, such as antioxidant, immune regulation, anti-stress, anticancer, neuroprotective and antidiabetic activities [[7], [8], [9], [10], [11]]; LBPs can improve the whole-body health status of mice and stimulate the expressions of IL-2, IL-12 and TNF-α,
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br The amygdala complex The amygdala complex is composed of
2021-03-11
The amygdala complex The amygdala complex is composed of distinct nuclei and subdivisions including the lateral (LA), basolateral (BL), and basomedial (BM) amygdala; the medial (Imp), lateral paracapsular (lpc), and main intercalated cell cluster (IN); and the lateral and medialcentral amygdala (
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Flexible alignment of isopropylphenylaminobenzimidazole with
2021-03-11
Flexible alignment of 7-isopropylphenylaminobenzimidazole 16 with the lead ursolic acid 1 was performed using MOE. It was found that the aryl group of compound 16, exemplified as a yellow circle in Figure 2, overlapped well with the corresponding alkyl chain of compound 1 as well as the other key f
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Building applications by selecting and integrating component
2021-03-11
Building applications by selecting and integrating components is known in software engineering as COTS-based development. Nowadays, this approach is recognized as a crucial success factor for the software industry (Ahuja, 2014). The advantages of using COTS components include minimizing the overall
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It is interesting that of the control
2021-03-11
It is interesting that of the control groups, female TG controls only had significantly higher MB-COMT protein than non-TG male controls (Supplemental Table 9, P = 0.005), while these two groups have almost equal expression of S-COMT protein (8.54- vs. 8.34-fold) and their COMT enzyme activity is al
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nitric oxide synthase inhibitors Our previous studies have s
2021-03-11
Our previous studies have shown that in a preimplantation mouse embryo the proportion of inner to outer cells (i.e. precursors of ICM and TE, respectively) is regulated by a different frequency of differentiative cell divisions at the 8- and 16-cell stages. Low number of inner blastomeres generated
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From an industrial perspective the low turnover numbers and
2021-03-11
From an industrial perspective, the low turnover numbers and limited substrate scope of α-KG halogenases still represents a significant challenge. However, in light of the fact that currently no chemical processes are available for the selective halogenation of aliphatic carbon centers in complex mo
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Introduction Collagen fibrillogenesis the assembly of
2021-03-11
Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the integrity of the whole tissue. Even a single point
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Because sex steroids and growth hormone play
2021-03-11
Because sex steroids and growth hormone play an important role in the development and maintenance of hepatic CYP450 enzyme expression and ER expression, it is possible that exposure to endocrine active agents during gestation and perinatally could alter expression of these proteins. Therefore, these
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In summary we elucidated the in vitro
2021-03-11
In summary, we elucidated the in vitro activities of KDM1B in regulation of PC cell proliferation and apoptosis. These studies provided a novel insight into the previously unrecognized roles of KDM1B in human PC cells. We showed for the first time that KDM1B knockdown attenuated proliferation and in
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In another study Nutlin a mediated p activation induced
2021-03-11
In another study, Nutlin-3a-mediated p53 activation induced strong negative impact on NF-κB signaling in LPS-stimulated neutrophils and macrophages [34]. Nutlin-3a limited cellular immune response to LPS, partly by attenuating DNA binding activity of NF-κB and impairing transcription of its target c
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Substitutions on the benzene ring of the
2021-03-10
Substitutions on the benzene ring of the phenyl acetic Verapamil HCl receptor moiety were evaluated to study their effect on DP and CRTH2 selectivity (). Compound has strong affinity for CRTH2, but it only has moderate affinity for DP. Small substitutions such as methoxy () and fluorine () next to
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CRF and urocortin produce marked effects on the cardiovascul
2021-03-10
CRF and urocortin 1 produce marked effects on the cytidine when administered both i.v. or directly into the CNS (Parkes et al., 2001). Systemic i.v administration of CRF and urocortin 1 cause a marked and long-lasting reduction in mean arterial blood pressure in rats Briscoe et al., 2000, Lawrence e
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Alternatively procedural factors may have contributed to the
2021-03-10
Alternatively, procedural factors may have contributed to the conflicting results. For instance, in order to have a more circumscribed area of drug diffusion, a volume of 0.05μl was injected in experiment 1b, which is four times lower than the one used in the mentioned plus-maze investigation. Besid
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