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Appropriate management of TLS includes risk assessment
2018-11-02
Appropriate management of TLS includes risk assessment, fluid management for TLS prophylaxis, and drug therapy. Fluid management is the key to TLS prevention. Aggressive hydration and maintenance of normal urine output are important in decreasing uric Stem Cell Compound Library deposition in the re
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The operative results of the
2018-11-02
The operative results of the patients in the three groups are summarized in Table 2. There were no statistically significant differences in the operative time between Groups II and III. Nevertheless, the operative time in Group II or III was longer than that in Group I (p return to normal activity
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pramipexole dihydrochloride br Case report An year old man p
2018-11-02
Case report An 80-year-old man presented with a large recurrent anterior abdominal tumor with central necrosis and discharge (Figure 1). The patient had undergone two tumor resections in the past 5 years. Computed tomography revealed a lobulated, heterogeneous mass (11.8 cm × 5.3 cm × 8.8 cm) at
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br Conclusion Since the discovery of IAHCs in the early
2018-11-02
Conclusion Since the discovery of IAHCs in the early 20th century and of HSCs about 50years later, a tremendous amount of work has been performed to understand their nature, origin and fate. The connection between HSCs and IAHCs has been established, as well as their direct endothelial origin. Ho
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br Materials and methods br
2018-11-02
Materials and methods Results The supplemental file 2 shows a schematic time-line of study design. Discussion NSCs are stem buy GSK-3 Inhibitor IX in the nervous system that can self-renew and give rise to differentiated progenitor cells to generate lineages of neurons as well as glia, suc
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Introduction The vascular endothelium the single cell
2018-11-02
Introduction The vascular endothelium, the single-cell layer lining blood vessels, is a multifunctional interface that displays a striking phenotypic plasticity necessary for maintaining vascular homeostasis. In this context, the vascular endothelium is critical to initiate an inflammatory response
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While the in vivo significance of our in vitro
2018-11-02
While the in vivo significance of our in vitro findings was examined in xenograft and metastasis studies, we observed a dramatic suppression of tumor growth and metastasis of SW480 CRC ddr1 by EDA silencing, which is associated with increased apoptosis and reduced expression of a cell proliferation
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For live cell imaging we established a well plate
2018-11-02
For live-cell imaging, we established a 96-well plate-based screening assay to assess expression of the pluripotency-associated surface marker TRA-1-60, a more reliable and specific marker for predicting successful reprogramming and iPS cell derivation than other markers including AP (Mali et al., 2
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In addition we observed significantly elevated levels
2018-11-02
In addition, we observed significantly elevated levels of synapsin and dopamine in Parkin cultures, although the changes in PINK1 cells did not reach statistical significance when compared with control iPSC- or ESC-derived floor-plate mDA neurons. Increased DA levels may appear, in contrast to the w
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br Results br Discussion We generated a
2018-11-02
Results Discussion We generated a library of iPSCs from patients with sickle cell anemia of diverse ethnicities and HBB haplotypes to study the biology of these ras pathway and the feasibility of their generation from blood samples collected from patients in distant locations and shipped froz
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Here using hNPCs derived from RTT patient iPSCs as
2018-11-02
Here, using hNPCs derived from RTT patient iPSCs as an example, we have shown that our method of hypoxia-mediated rapid astrocytic differentiation of hNPCs can be applied to functional analysis of patient-derived astrocytes. We revealed that MECP2 MT astrocytes diminish the soma size, neurite outgro
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hcv virus The structure of La SrMnO LSMO x is
2018-11-02
The structure of La1–SrMnO3 (LSMO-x) is far from cubic perovskite. According to Ref. [7], this structure has two types of distortions, which are caused by either the mismatch between the size of the cations and the size of the corresponding free space (type 1), or by the Jahn–Teller (JT) effect (typ
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The mixture of pure nanoparticles of the
2018-11-02
The mixture of pure nanoparticles of the influenza virus (strain A1-H1N1) and albumin proteins (as an example of impurity) can be considered as a model of dispersions in the technological process of vaccine production. The influenza virus particle was approximated as a homogeneous sphere with the me
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To determine whether economic psychological and
2018-11-02
To determine whether economic, psychological, and neighborhood indices explain excess risk by race/ethnicity in high AL, we fit a series of linear regression models, with results displayed in Tables 3 and 4. We focused on the proportion of excess risk in high AL by race/ethnicity that was explained
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Risk behaviours are important threats during
2018-11-01
Risk behaviours are important threats during adolescence due to possible lifetime negative consequences. Their prevalence is high in the USA: the percentage of those who ever smoke, drunk, use marijuana and cocaine was respectively 44.7, 70.6, 39.9 and 18.2% in a national survey; the percentages of
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