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br Discussion Digoxin has multiple effects on the myocardium
2019-04-26

Discussion Digoxin has multiple effects on the myocardium and has multiple cardiac-related uses. In the treatment of atrial fibrillation, digoxin increases vagal tone to prolong the refractory haspin inhibitor at the AV node, decreasing ventricular response to higher atrial rates [3]. Toxic dose
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In the largest published case series Rossi et
2019-04-26

In the largest published case series, Rossi et al. identified seven cases of infant B-ALL, including three cases of congenital leukemia, with lineage switch from B-lymphoid to myelomonocytic leukemia [12]. An additional two cases were described with a switch from AML M5 to B-ALL. Of the nine describ
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Many studies over the past years have shown the
2019-04-26

Many studies over the past 20 years have shown the potential of urinary markers in the detection of the presence of bone metastases [3–11], the use of urinary markers for its prognostic value in bone disease [2,4,12–20], as well as directing therapy for bone metastases patients [2,6,12–18,21–25]. Th
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br Conclusions br Disclosures br Funding Sources br Introduc
2019-04-26

Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r
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Our patient a year old woman
2019-04-25

Our patient (a 24-year-old woman) arrived in Italy from Eastern Europe in March 2013 as an illegal immigrant. Three months later she was admitted to our hospital. Her blood counts were as follows: leukocytes 410.7×109/L, platelets 391×109/L, Hb 11g/dl, with immature myeloid tyrosol at differential c
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(S)-Crizotinib br Mega cohort studies Remote monitoring coll
2019-04-25

Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise
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Since antithrombotic therapy for patients with AF is rapidly
2019-04-25

Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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br Methods br Results br Discussion br Conclusions
2019-04-25

Methods Results Discussion Conclusions Conflict of interest Acknowledgments We thank Mr. John Martin for his linguistic assistance, and Mr. Jiro Suto for technical assistance in developing the QRS-T subtraction program. This study was supported by the Fukuda Foundation for Medical
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All these receptors tightly control tissue
2019-04-25

All these receptors tightly control tissue homeostasis, and any dysregulation of these ligand–receptor systems (mutations, overexpression, etc.) disturbs cell communication and leads to pathological situations. Bone formation and bone remodelling are then controlled by a large panel of cytokines and
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The GCT usually involves a cladding that consisted
2019-04-25

The GCT usually involves a cladding that consisted of reactive bone and fibrosis, with a distinct boundary surrounded by soft tissue. Nevertheless, the active cladding is very thin among patients with severe invasiveness, including tumors that extend directly in into the muscle and fat, or other sig
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br Materials and methods Fifteen
2019-04-25

Materials and methods Fifteen healthy adult men participated in this study. The left anterior chest area was subdivided into 15 regions based on 5 longitudinal points (from the second to the sixth intercostal spaces) and 3 lateral points (including the left sternal border, midclavicular line, and
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br Alternans and arrhythmogenesis in different clinical cond
2019-04-25

Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a
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br Discussion Sato et al first reported TCM
2019-04-24

Discussion Sato et al. [11] first reported TCM in 1990, and thereafter, numerous cases were reported in the late 2000s. In 85% of the cases, TCM onset was preceded by an emotional or physical stress event, however, in 15% of the cases, the presence of a stress trigger could not be detected [2]. M
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EZ Cap Reagent GG (3\' OMe) A year old man was admitted
2019-04-24

A 49-year-old man was admitted to our hospital for SMVT treatment. He was diagnosed with DHCM at the age of 45 years in the referring hospital. His chief complaint was palpitations, and he was conscious and hemodynamically stable during the VT. A 12-lead electrocardiogram (ECG) during sinus rhythm r
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There are few learning points that can be
2019-04-24

There are few learning points that can be derived from this case. While VDD is an acceptable mode in young patients, one should be cautious of using this mode in elderly patients with sick sinus syndrome, unless retrograde VA conduction is absent. A single PVC can trigger a ventricular paced rhythm
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